Working product – Urabandai SS http://urabandai-ss.com/ Sat, 19 Nov 2022 06:24:10 +0000 en-US hourly 1 https://wordpress.org/?v=5.9.3 https://urabandai-ss.com/wp-content/uploads/2021/09/cropped-icon-32x32.png Working product – Urabandai SS http://urabandai-ss.com/ 32 32 Shark Tank Season 14 Episode 7 Companies and Products https://urabandai-ss.com/shark-tank-season-14-episode-7-companies-and-products/ Sat, 19 Nov 2022 06:24:10 +0000 https://urabandai-ss.com/shark-tank-season-14-episode-7-companies-and-products/

First in the tank this week on Shark Tank are entrepreneurs from West Palm Beach, Florida who guarantee their artisan cheese and charcuterie board delivery business will impress and be the perfect party favor for any event. Los Angeles Entrepreneurs Showcase Their Line of Subscription Products Designed to Keep Cars Cool and Vibrant While Driving; while brothers with an affinity for action sports from Traverse City, Michigan hope to lead the way with their sleek sports equipment lighting kit designed to keep people safe at night. Last into the Tank is a St. Clair Shores, Michigan entrepreneur who delivers the ultimate shaving experience with their all-in-one solution designed to refresh and improve all shaving needs.

The Sharks in this episode are Mark Cuban, Kevin O’Leary, Lori Greiner, Barbara Corcoran and Robert Herjavec.

Boardmaking
boarderie.com
Boarderie is the first company in the world to ship deli-grade, pre-arranged cheese and charcuterie boards directly to customers’ doorsteps, nationwide. Boarderie’s team of experts spent 20 years in fine dining hospitality and special events before the pandemic forced them to pivot. Two years later, they’re defining a whole new category in edible gifts and e-commerce catering with perfectly matched, impeccably sourced pasture displays that are deliciously simple to send. After two record-breaking first years and a feature on Oprah’s Favorite Things 2022, they’re just getting started!

Mount FRSH
ridefrsh.com
Ride FRSH is a unique and stylish car air freshener brand that is dramatically improving the industry. With our monthly subscription, exclusive licensed products and a selection of super sweet fragrances, we’ve changed the experience behind buying and using car air fresheners!

action glow
actionglow.com
ActionGlow is an innovative LED lighting system that can be applied to any brand of sports equipment. With apps for snowboards, skis, surfboards, longboards and more, ActionGlow is pioneering a whole new way to participate in action sports after the sun goes down.

Legacy Shave
legacyshave.com
Legacy Shave innovation and patents will change the global shaving industry. With an idea they had more than 28 years ago with their father, brothers Mike and Dave brought this invention to market, patented this idea and named their company in honor of their father and the legacy with this idea…hence the name Legacy Shave. Legacy Shave is a modern shaving brush for modern times. Same benefits as your grandfather, but modernized to work on most spray cans. Working with foam and gel shaving boxes, even up to travel sizes, the Legacy Shave customer now enjoys a salon shaving experience in the comfort of their own home on every shave while saving money. time. Closer shave with less mess and waste. Legacy Shave changes everything you hate about shaving and makes a great gift for any occasion.

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How product co-creation studio FirstBuild is changing the way new things are made – TechCrunch https://urabandai-ss.com/how-product-co-creation-studio-firstbuild-is-changing-the-way-new-things-are-made-techcrunch/ Sun, 13 Nov 2022 19:41:13 +0000 https://urabandai-ss.com/how-product-co-creation-studio-firstbuild-is-changing-the-way-new-things-are-made-techcrunch/

Crowdfunding, crowdsourcing and small-batch production for the win

If you are in charge of R&D at a major manufacturer of household appliances, you have a challenge to meet.

You typically produce products in huge quantities with pretty slim margins. In order to recoup your development, tooling, and launch marketing costs, you must create and sell a large number of products. To make sure this is possible, you’ll probably end up doing a bunch of user and market research to make sure you have the best chance of success with your products.

It makes sense, but the business model itself means it’s hard to do anything really risky, which means traditional manufacturers rarely come up with anything truly innovative.

If there was a mushroom fruiting device, would many more people regularly grow mushrooms at home? There was only one way to find out: build one and try to sell it.

This is where FirstBuild comes in. If you’re a small appliance nerd, you might have seen its Opal Nugget ice maker, the studio’s first big breakthrough; the Mella mushroom fruiting chamber; its indoor pizza oven; or the Arden Indoor Smoker. I spoke with André Zdanow, President of FirstBuild, to understand where these ideas came from and how the studio is working to try to replicate these successes.

“The most famous example is probably the Opal Nugget ice maker. At first it wasn’t a product at all – it was a technology that the refrigeration division of GE Appliances was working on,” Zdanow said, explaining that it turned out to be a headache. They wanted to put the “nugget of ice” in a refrigerator, but were unable to determine exactly how big the market would be for such a thing. “It’s actually very complicated to put technology in a fridge. In other words, it really was a great idea that engineers had been toying with for years, but in the context of the direction and economics of a multi-billion dollar company, it wasn’t something they could focus on.

The Opal nugget ice maker was FirstBuild’s first commercial success. Picture credits: First build

In a parallel universe, this technology would never have seen the light of day, but instead the engineers came to FirstBuild and wondered what would happen if they put the technology in a separate device, rather than a refrigerator. full size.

“We see a lot of people going to the store and buying this type of ice cream. They call it sonic ice or hospital ice. We decided to develop a prototype and see if people want it to be just an ice maker,” Zdanow explained. This was the genesis of the success of the FirstBuild laboratory. “It all started with rudimentary concepts that looked like an ice maker, but contained nuggets of ice. From there it progressed through industrial design and eventually to a $2.7 million crowdfunding campaign on Kickstarter in 2015.”

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Will set up Matter lab in India if demand increases: CSA CEO https://urabandai-ss.com/will-set-up-matter-lab-in-india-if-demand-increases-csa-ceo/ Thu, 10 Nov 2022 19:29:29 +0000 https://urabandai-ss.com/will-set-up-matter-lab-in-india-if-demand-increases-csa-ceo/

NEW DELHI, TECHNOLOGY COMPANIES, APPLE, AMAZON, GOOGLE : In 2019, big tech companies such as Apple, Amazon and Google, who otherwise strive to lock users into their own ecosystems, made an unprecedented decision. Hundreds of companies have come together to create a universal smart home standard, which would simplify smart homes and make them available across multiple ecosystems like iOS, Android, and Alexa. The standard, called Matter, launched earlier this week with partners including Amazon, LG, Samsung and Ikea. In an interview, Tobin Richardson, President and CEO of the Connectivity Standards Alliance (CSA), which created Matter, explained how a single standard is meant to become a common thread for smart devices around the world. Edited excerpts:

How many companies does Matter currently work with and how many products are there on the market?

As an alliance, we worked with approximately 550 companies to develop an interoperability standard. The standard took three years to develop.

On October 4, the day we launched the specification for the standard, we had approximately 108 products that were tested against our standard.

By the time we launched Matter 1.0, that number had grown to 190, and today we have at least 238 certified smart homes and connected devices under our network.

Why are Big Tech platforms looking to open access now?

Even large tech companies today see the limits of a closed ecosystem. While each of these companies continues to see growth of their own smart home products, they wouldn’t be at the same scale that they can potentially see with a standards-based approach.

Will it benefit small businesses that don’t have the same means as big tech companies?

Even if a brand has two engineers, they must be able to use our software development kit (SDK), as well as our partner relationships, to move from concept to product.

It also helps set a quality bar that you expect from a smart device, so that it’s no longer just a low-cost device, but one that meets a standard.

More than 3,000 engineers from 280 companies participated and provided technical support to develop the Matter standard.

For small businesses, it is nearly impossible to access such a breadth of technical support on their own.

How does the validation process work and what options do companies have in India?

There are several ways, depending on the size and level of the candidate company. Suppliers can seek partners within the Matter network, negotiate their terms and find their own common ground.

We then have one of the accredited testing labs to test the products, which then relays to the CSA, and the product is certified accordingly. We also have a mechanism if a company finishes a product and seeks to white label it for other brands to sell, which can bring a wide variety of new products to new markets where adoption is still low. We have nine authorized labs at the moment, and we have selected 18 different locations to facilitate these labs.

We don’t have any in India at the moment, and we are working on it at the moment. In Asia, we have one in China.

The configuration of these labs is based on demand, and we expect larger capacities to be rolled out over time. I can’t specify a timeline right now, but as market demand grows in different regions, we will help set up more facilities accordingly.

Catch all the company news and updates on Live Mint. Download the Mint News app to get daily market updates and live trade news.

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New rules loom as baseball pushes for better product in 2023 https://urabandai-ss.com/new-rules-loom-as-baseball-pushes-for-better-product-in-2023/ Sat, 05 Nov 2022 23:26:38 +0000 https://urabandai-ss.com/new-rules-loom-as-baseball-pushes-for-better-product-in-2023/

In other words, a lot of the game is spent waiting for something to happen on the field.

Major League Baseball hopes that the end of the series will also mark the end of this era of baseball with the rule changes that will be instituted starting next season.

They include a pitch timer that will require the pitcher to begin their motion within 15 seconds when the bases are empty and up to 20 seconds with at least one runner.

Teams will need to keep two infielders on either side of second base, and all four must have both feet on the infield when the pitcher is on the rubber. Infielders also cannot change sides.

How well the new rules, especially the pitch clock, will work will depend on how quickly the referees enforce them. It’s something the league can control.

They have no control over the amount of pushback from players. The four players on MLB’s 11-person competition committee actively refined the new metrics, but ultimately voted against the clock and shift rules.

“I’m always concerned that when we go through a period of change it’s going to be difficult for the players,” commissioner Rob Manfred said on Sirius XM radio last week. “I think one of the things I took away from the trip around talking to the players is that you understand very well that it’s their livelihood.

“Any change they feel is a threat to the continuity of their career. But hopefully these changes, they can adapt to it fairly quickly and we won’t have any problems with the changes next year. Overall, I think the changes are critically important to our game.”

Average playing time this season was 3 hours and 44 seconds, down from 3:03.44 in 2021. This drop was attributed to the use of Pitch Com devices to transmit signals from catcher to pitcher via a small top -speaker.

A pitch timer should drop the average playing time below three hours for the first time since 2011 (2:56).

It could also reduce the growing advantage of pitchers over batters. Pitchers are trained to take their time between pitches and muster their energy to pitch with the greatest speed possible. Less time between pitches will mean more fatigue, less speed and theoretically less strikeouts and more offense.

A pitching clock could encourage a throwback to when pitching was more of an art than a showdown. In July, new Hall of Famer Jim Kaat said he believed the stopwatch would lead pitchers to work with better pace and find different benefits beyond speed.

For now, MLB will maintain a roster of 26 players with a maximum of 13 pitchers. The league is considering bringing it down to 12, which would reduce the frequency with which teams use relievers.

Baseball is also expected to retain the rule of having a “ghost runner” on second base to start extra innings.

“We haven’t finalized that,” Manfred said. “My strong feeling is that we are going to have him again. The clubs like it, the players like it. And I think overall the fans like it. I think it sort of emphasizes the end of the baseball game in a way that was positively received.

The rule is not used during the playoffs.

“During the regular season, I like it,” Phillies manager Rob Thomson said. “In the playoffs, I don’t. I think you play baseball.

Astros manager Dusty Baker is also in favor of the rule.

“It saves your pitching as much as anything,” he said.

Purists railed against the rule. But it calls for strategy.

“It makes you play a different game at home than on the road,” Baker said. “At home you can bunt, you can play for that single point. On the road, a race doesn’t mean much.

“It can mean something. But basically they have the ability to tie it, so you can go back and forth, back and forth. So you’re probably not playing for the big inning, but probably for a twisted number on the road, where at home you get last at bat and that could be the game.

As the teams prepared for Game 6 on Saturday night, the new rules weren’t the focus. But this time next season the game will have a new look.


Peter Abraham can be contacted at peter.abraham@globe.com. Follow him on Twitter @PeteAbe.

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Aurora says it has enough money to bring self-driving trucks to market by 2024 – TechCrunch https://urabandai-ss.com/aurora-says-it-has-enough-money-to-bring-self-driving-trucks-to-market-by-2024-techcrunch/ Thu, 03 Nov 2022 00:21:56 +0000 https://urabandai-ss.com/aurora-says-it-has-enough-money-to-bring-self-driving-trucks-to-market-by-2024-techcrunch/

Autonomous vehicle technology company Aurora Innovation released its third-quarter earnings report after the bell on Wednesday. The company ended the quarter with approximately $1.2 billion in cash and short-term investments, which Aurora says will be enough to reach commercial launch in mid-2024.

These claims came just days after former competitor Argo AI went out of business and Mobileye went public with the third most successful IPO of the year. These two moves are a sign that automakers who were once willing to invest billions in the development of audio-visual technology without short-term profit gains are now turning their attention and resources to short-term profit centers like systems. advanced driver assistance systems in passenger-owned vehicles. . So the question becomes, can Aurora hang on?

CFO Richard Tame said on the investor call that Aurora will need to raise more funds, but the company didn’t tell TechCrunch whether that would happen before or after the 2024 launch. (However, in a memo leaked in September, CEO Chris Urmson wrote to Aurora’s board that it was helpful to find a “pathway to raise $300 million next year to add about six months to our track.” .) Given the current economic situation and Aurora’s cash burn history, the company may be able to make it through 2024 with the funds it currently has, but only narrowly – and only if it keeps costs down. line.

During the third quarter, Aurora’s operating loss totaled $200 million, up from $128 million in the same quarter last year, but down from to losses of nearly $1.2 billion from the second quarter of 2022. If the startup was able to sustain a net loss of $200 million from the fourth quarter through the first quarter of 2024, it wouldn’t have need to raise more cash before commercial launch. But as a pre-revenue startup working on cutting-edge technology, Aurora will incur huge R&D costs to scale and bring its product to market. Additionally, Aurora should somehow avoid being hit by inflation and supply chain constraints. The result ? Aurora will need to find efficiencies at all levels.

The leaked memo also outlined a range of cost-cutting and cash-generating options for Aurora’s board, including a hiring freeze, potential layoffs, asset divestiture, privatization and even selling to leading tech companies. Aurora didn’t mention any of these potential realities during its earnings call, but that doesn’t mean they aren’t on the table.

The street responded favorably to Aurora’s attempts to appease investors. The company’s stock is up 5.85% after the market close.

Aurora has prioritized bringing self-driving freight to market through a series of pilot partnerships with FedEx, Paccar, Schneider, Werner and Xpress. But the company is also working with Toyota to eventually launch a subscription service for the ride-sharing market. Earlier this year, the company unveiled its test fleet of Toyota Siennas that were custom-built for robotaxi operations. In the third quarter, Aurora recognized approximately $3 million in collaboration revenue from Toyota.

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Top Trademark Lawyer Shares the Importance of Protecting Intellectual Property as a New Business Owner https://urabandai-ss.com/top-trademark-lawyer-shares-the-importance-of-protecting-intellectual-property-as-a-new-business-owner/ Sun, 30 Oct 2022 11:30:00 +0000 https://urabandai-ss.com/top-trademark-lawyer-shares-the-importance-of-protecting-intellectual-property-as-a-new-business-owner/

New entrepreneurs make a big mistake when developing their brand: they save the brand until the last step.

More than 650,000 patent applications were filed with the U.S. Patent and Trademark Office in 2021, down slightly from 653,311 the previous year. However, with thousands of trademark disputes filed every year, first-time business owners must prioritize trademark logos and wordings to avoid a hefty fine.

Rosezena Pierce, founder and CEO of RJ Pierce Law Group, has often seen entrepreneurs make this costly mistake. With over ten years of experience and more than 3,200 registered trademarks, she and her team help business owners protect their brands. His portfolio includes celebrities such as Twista and Sierra Gates. Additionally, the company is ranked among the top 50 trademark companies in the country.

“The biggest misconception is that you can wait to do it until later,” says Pierce. “People think they have to do all these other things first. Then the trademark is something they can revisit later when it’s the complete opposite. I always ask people, ‘Will you build a house on land you don’t own?’ A lot of times people think, “Oh, I have to get my LLC first. I need to get my bank account and EIN number. I need to collect my product packaging or marketing materials. And then I have to make money. Then I will think about the brand.

Here’s the thing, you can do all of this first. But if someone tracks that name you just attached to that LLC, that bank account, or those products, packaging, or marketing materials, they’re sending you a cease and desist letter. Now they demand that you give them product packaging or marketing materials. You may have wasted the money, time, and resources you invested in building a new brand.

When Pierce started law school, she already had two children, and during her last semester she gave birth to a baby girl. She had the opportunity to stay home and study for bar, which made her realize that she loved being home with her children. At the time, she met a mentor who taught her how to start her own law practice; he helped her see how she could represent underserved small business owners.

Pierce marketed his services on social media and attended business networking events. Through her connections, she met managers, assistants, and celebrity friends who helped her grow her company’s entertainment vertical. Over the years, Pierce has gone from working with clients to being the face of the company through speaking engagements and educational workshops.

“It was time for me to think about growing the business,” smiles Pierce. “I changed my mindset to say, ‘Okay, it’s time to grow this business. I can’t be in everyday life. I have to get out of this and have a team of leaders.

Pierce emphasizes the importance of creating a distinctive name when creating a brand or product; the more unique it is, the better the chances of receiving the mark. Additionally, using original wording will deter competitors from using the same; when descriptive terms are used, there is a higher likelihood that others in the same industry will also use the same detailed wording.

Many new business owners think they are legally protected if they add a trademark symbol to their brand. However, the opposite is true. All the symbol does is show that you were using it, and most likely in the application process. It is only when the USPTO approves the application and issues the trademark that a name or logo is legally protected.

As Pierce continues to expand her business and her transition as a leader, she is focused on the following critical milestones:

  • Make sure you are comfortable with your decision. Take the time to research and navigate the new vertical you are pivoting to.
  • Create a different platform of who you want to be that will attract future clients or employers.
  • Be confident in your decision. Speak with authority when you share your next move, it builds buy-in.

“I believe there are so many entrepreneurs trying to become leaders and CEOs,” Pierce concludes. “I believe that as good leaders, we understand that we don’t have to be the smartest people in the room; we need to hire experts.

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Amazon and Starbucks votes show workers are ambivalent about unions https://urabandai-ss.com/amazon-and-starbucks-votes-show-workers-are-ambivalent-about-unions/ Sat, 22 Oct 2022 19:17:38 +0000 https://urabandai-ss.com/amazon-and-starbucks-votes-show-workers-are-ambivalent-about-unions/

Comment

In the latest labor wars news, workers at a Starbucks in Portland, Maine have just voted to unionize, while those at an Amazon warehouse in upstate New York have ​voted against. Opinions on the value of unions obviously differ and passions run high. As an economist, I try to rationally assess these kinds of questions. Here is my attempt to explain what I think of unions.

The case for unions begins with the possibility of higher wages: unionized workers enjoy a wage premium of 10% to 20% (although many of these estimates are dated and globalization may have made the premium much higher low, in some cases close to zero). Unions can also provide workers with a more effective way to air grievances in the workplace and help them coordinate better services with their employers.

The more skeptical view of trade unions accepts the logic of these arguments, but questions the extent of the associated benefits. The union wage premium is good for the workers who receive it, of course, but it also drives up prices. Other workers in turn pay these higher prices. Thus, the net return to all workers is less than the wage premium suggests.

It’s not that labor costs and retail prices move exactly in tandem. If labor costs increase by 12% but labor is only a small part of the marginal cost of the product, prices can increase by much less than 12%. But if labor is only a small part of the cost, unions are less likely to be involved. The greater the role of workers, the more likely it is that increases in union wages will translate into increases in retail prices.

Workers as a whole can still benefit from unions if the burden of rising prices falls largely on the wealthy. This may be the case for fancy diamonds or expensive restaurants, but historically unions have been more common in industries that provide goods and services to the middle class, such as automobiles.

Another question is whether higher wages for workers lead to greater automation and therefore lower demand for labor in general. The US manufacturing industry has automated significantly over the past few decades and accounts for a shrinking share of US employment. Automation is also coming to Amazon warehouses. Additionally, many formerly unionized jobs have gone overseas rather than to robots.

It is difficult to trace the causal impact of unions in this area, as there are so many other factors at play. Nevertheless, it is plausible that higher union wages hurt some non-union workers, by reducing labor demand in unionized sectors. It should also be noted that management tends to be hostile to unions, and part of the reason may be that unionization will lead to lower profits. And lower profits will eventually mean lower investments.

Even taking all these factors into account, it is still possible that unions benefit workers overall. But only to a modest extent. This would not be a reason to make unionization a top priority or to place unions at the center of a theory of what improves the situation of workers.

Additionally, the union wage premium—as opposed to a union wage increase, which is negotiated every few years—is a permanent change in an industry or sector. In the longer term, productivity improvements (or lack thereof) are more important than the wage premium.

What about working conditions? Here again, union negotiation can be useful, whether adversarial or cooperative. Again, however, the benefits will likely be modest. Better working conditions are another form of higher pay and come with the costs associated with higher wages that I mentioned earlier.

There is also the question of the importance of trade unions in improving working conditions. Working conditions in the United States have improved steadily over the years, even as the United States has seen a drastic drop in unionization rates. Unions are therefore probably not the main factor behind many improvements for workers.

Unions perform useful functions in a market economy, and no one should demonize them. At the same time, at least for this economist, it is a mistake to consider the unions as the savior of the working class.

More from Bloomberg Opinion:

• Unions have not kept up with the new economy: Allison Schrager

• Why companies could learn to love unions: Conor Sen

• Workers of the World Unite Again: Chris Bryant

This column does not necessarily reflect the opinion of the Editorial Board or of Bloomberg LP and its owners.

Tyler Cowen is a Bloomberg Opinion columnist. He is a professor of economics at George Mason University and writes for the Marginal Revolution blog. He is co-author of “Talent: How to Identify the Energizers, Creatives and Winners in the World”.

More stories like this are available at bloomberg.com/opinion

]]> JPMorgan Chase offers advance payday deposits to Secure Banking customers https://urabandai-ss.com/jpmorgan-chase-offers-advance-payday-deposits-to-secure-banking-customers/ Wed, 19 Oct 2022 12:07:00 +0000 https://urabandai-ss.com/jpmorgan-chase-offers-advance-payday-deposits-to-secure-banking-customers/

Signage outside a Chase bank branch in San Francisco, Calif., Monday, July 12, 2021.

David Paul Morris | Bloomberg | Getty Images

JPMorgan Chase gives select customers early access to their direct deposits, a feature popularized by fintech rivals as it hopes to lure users into an overdraft-free checking account.

The bank is enabling the feature – which speeds up payments including payroll, tax refunds, pensions and government benefits by up to two days – to customers of its Secure Banking product starting this week, according to Ryan MacDonald , Head of Growth Financial Products for Chase .

That usually means getting paid on a Wednesday rather than a Friday, he said.

“Those few days are often the difference between digging for money from family or not paying that bill on time and being charged late fees,” MacDonald said in an interview.

JPMorgan, the largest U.S. bank by assets, hits the milestone as the sector faces mounting pressure from regulators and lawmakers over overdrafts and other fees. While smaller rivals, including Capital one said they were dropping the overdraft fee, the CEOs of the three largest US institutions have repeatedly refused calls to end the fee.

Instead, banks have drawn attention to existing products that protect users from overdraft fees, while providing most of the features of full-service accounts.

For JPMorgan, that product is Secure Banking, which has no minimum balance requirement and costs $4.95 per month. The service, which is aimed at households earning about $55,000 or less a year, has about 1.4 million users, MacDonald said. Most customers have direct deposit and will automatically start receiving advance payments, he added.

The bank, which says it serves more than 66 million U.S. households overall, can be a “fast follower” to fintech rivals when they build much-needed functionality, MacDonald said. Startups such as Chime and Current popularized early direct deposits, winning millions of cost-conscious users.

“Fintechs are doing a good job of entering the space and trying to disrupt by offering services,” MacDonald said. “Customers didn’t even think about early payment access until some of these players arrived. As we’ve assessed, we think there’s a real need for some customers to have this. .”

The bank is working on introducing other solutions for this group, including small loans or installment products, to help users smooth out their financial needs in times of emergency, he said.

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What treatments work for women with thinning hair? https://urabandai-ss.com/what-treatments-work-for-women-with-thinning-hair/ Mon, 17 Oct 2022 11:54:01 +0000 https://urabandai-ss.com/what-treatments-work-for-women-with-thinning-hair/

Jennifer N. Choi is division chief of medical dermatology and oncodermatology at Northwestern University Feinberg School of Medicine.

Q: Are there any treatments that actually work for women with thinning hair?

A: Topical minoxidil, often known by the over-the-counter brand name of Rogaine, is my first choice treatment for the most common cause of thinning hair in women: female androgenetic alopecia (GAA).

Not only is topical minoxidil the most studied treatment available, it is also the only topical product that has been approved by the FDA for the treatment of AGA.

If you have noticed hair loss, the first step to take is to get a diagnosis from a primary care doctor or dermatologist, who can perform a scalp biopsy and order blood tests to look for potential causes, such as anemia or thyroid disorders.

But if your hair loss was gradual and started to widen on your side, with your frontal hairline still intact, you probably have AGA. It can start anytime after puberty and becomes more common as women get older. By age 70, up to 50% of women have some degree of AGA. Whites are more likely to be affected, followed by Asians and Blacks. If your mother or father has AGA, you are more likely to develop it.

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When it comes to treatments, patience and managing expectations are important. You have several options, including topicals, prescriptions, supplements, and procedures. But I advise my patients to wait at least six months before deciding if any of them are working.

Unfortunately, many women will still have thinning hair even after trying several treatments: there is no single solution and the chances of success vary in each case.

Here’s what you need to know about your AGM treatment options.

How should I use topical minoxidil?

Topical minoxidil is available in 2% or 5% strengths over the counter and can be applied once or twice daily. I generally recommend the 5% version as it has been shown to be more effective, but it also has an increased likelihood of side effects, such as scalp irritation, flaking, itching, and facial hair growth . Higher concentrations are available by prescription.

You can choose between a solution or a foam. The solution, which is applied with a dropper, can sometimes run down your face or leave your hair greasy. The foam has a more controlled application with your hands and it does not contain propylene glycol, which can cause irritation or allergy in rare cases. Both should be gently rubbed into the scalp – just be sure to wash your hands afterwards.

You should continue to apply topical minoxidil even after you see results. If you stop, you may notice hair loss from new growth within four to six months.

Ask a Doctor: Why Do I Shake Before I Fall Asleep?

What about oral minoxidil?

Oral minoxidil has traditionally been used to treat high blood pressure, but has been gaining a lot of attention lately as an off-label treatment for low-dose hair loss. More rigorous research is needed to confirm its overall safety and effectiveness, but in my practice I am using it increasingly in both men and women, with most experiencing at least some degree of noticeable growth. hair.

The studies are promising so far. A 2020 medical literature review found that 17 studies involving 634 patients showed it could help, but reported effectiveness varied widely: from 10-90% in terms of stabilizing hair loss, increasing overall hair density, improved hair thickness and decreased hair loss. Topical minoxidil has been shown to have reported efficacy in treating AGA in women ranging from 13-63%.

If you don’t like the mess of applying minoxidil topically or have had a reaction, talk to your dermatologist about taking the medication by mouth. I generally start patients on 1.25 milligrams or 2.5 milligrams daily, with room for higher doses if needed. It is only available by prescription and there are possible side effects including hair growth in places other than the scalp (such as the face), low blood pressure and swelling in the legs.

Other oral prescription medications that have been used to treat hair loss over the past 10-20 years are spironolactone, finasteride, and dutasteride. They haven’t been compared directly to oral minoxidil, so it’s unclear which is more effective, and women who can get pregnant shouldn’t use these drugs unless they’re using birth control methods. strict because they can cause fetal abnormalities. Finasteride and dutasteride are generally reserved for postmenopausal women for this reason.

The evidence is not as strong for supplements as it is for topical minoxidil.

My patients often ask me about two popular oral supplements: Nutrafol, which contains saw palmetto, and Viviscal, which contains a compound of marine extracts and polysaccharides. Many of the studies on these components and supplements have industry funding or interests, but they have suggested some effectiveness with few adverse effects.

Oral biotin supplements have long been touted to help with hair growth. But these high-dose supplements haven’t actually been proven to work.

Large-scale randomized clinical trials by independent researchers are always needed on supplements, but I occasionally mention Nutrafol and Viviscal – instead of regular biotin – to patients who want to try a supplement without a prescription, even though I can’t. promise that they will see significant results. .

Be sure to consult your doctor before trying any supplements, even if they are labeled as natural. For example, for breast cancer survivors taking estrogen-inhibiting drugs long-term, such as tamoxifen, certain supplements may interfere with the metabolism of the estrogen-inhibiting drug, potentially making it less effective.

Ask a Doctor: Why am I sleepy in the afternoon after eating breakfast?

What if none of these other options work?

You may want to consider trying one of these therapies or procedures, but they are usually not covered by insurance and can be quite expensive. There is no rigorous evidence yet that they will work.

Red light devices: These devices use low-level light therapy (LLLT) and come in different forms, such as a comb, hood, or helmet. The HairMax LaserComb is a portable, non-invasive device that has been FDA cleared for the safe treatment of male and female AGA with a starting cost of $199. I would recommend this treatment to highly motivated patients who can commit to using it at least three times a week – preferably in combination with another treatment, such as minoxidil – because it is easy to use, relatively affordable and generally considered Like on.

Platelet-rich plasma: Platelet-rich plasma (PRP) is a plasma preparation that comes from your own blood. Some small studies have suggested that PRP injections into the scalp might help some patients, but more rigorous evidence is needed, especially since the cost can be so high and the procedure can be painful. Three monthly sessions, followed by a maintenance period of three to six months, are generally recommended. The cost of each session is usually around $250 to $750. PRP also tends to be used as an adjunct therapy in combination with other treatments, and not everyone is a candidate.

Surgical Hair Transplant: If one of the therapies does not work, surgical hair transplantation is another option. Intact hair is surgically removed from a part of your scalp that still has thick hair, separated into units of individual hair follicles, and surgically transplanted into tiny holes on the part of the scalp affected by hair loss or thinning. hair. This procedure typically takes several hours at a time, requires local anesthesia, and can be very expensive – ranging from $6,000 to $60,000, depending on the amount of hair transferred, the technique used, and the experience of the surgeon – but many my patients have had very long term results.

Ask a Doctor: Do you have a health question? We will find the right expert to answer them.

]]> How Missing Traceability Data Could Affect Pharmacy Patients https://urabandai-ss.com/how-missing-traceability-data-could-affect-pharmacy-patients/ Fri, 14 Oct 2022 20:01:30 +0000 https://urabandai-ss.com/how-missing-traceability-data-could-affect-pharmacy-patients/

There are a number of obstacles related to distributors’ compliance with the requirements of the Drug Supply Chain Security Act (DSCSA), including:

  • They don’t have much time left to set up data exchange systems
  • Some smaller or less connected players may ignore the requirements and the need to prepare
  • The costs of implementing traceability systems can be prohibitive, especially without a way to recover funds directly

The 2022 HDA Traceability Seminar this week in Washington DC highlighted the efforts of the distributor (pharmacy) community. During a panel on distributor data flow, an audience member asked how data exceptions could affect patients in real time. In the scenario he described, a pharmacy tells a patient to come in at 10 a.m. when his prescription needs to be filled, but he discovers while trying to fill that he has not received traceability data for this product and he cannot fill the prescription.

[Editor’s note: Panelists spoke on this topic during the Q&A portion from the audience. As such, their statements were made off-the-cuff. They may include conjecture and do not necessarily reflect official policies.]

Leon Nevers is the Director, Sourcing and Business Development at HEB. He explained that when a pharmacist runs out of an item, there are usually opportunities to refill other items, whether by offering an over-the-counter drug or sourcing from a DSP. [distance selling pharmacy] according to customer needs. “As for the labor impact, I have a pharmacist who would just have to dispense a prescription to the customer any way they want. It’s a dissatisfaction for the customer when they don’t receive this, so that’s the first step. The second step is that the pharmacist now needs to go and counsel that customer and probably walk them down the OTC aisle or explain to them what their options are and now is the time,” he said.

If a given vendor causes these kinds of outages frequently, Nevers said he might have to consider moving that vendor’s product until he can get his data in shape and prove he can ship it. properly.

Lisa Schwartz, PharmD, RPh, senior manager, professional affairs, National Community Pharmacists, echoed that sentiment, adding that it would likely be treated as a “sold out” — although the product is in the facility, it cannot be distributed in a conforming manner. “You end up having to do an assessment of doing business with a business partner at some point,” she said. She also noted that at some point a pharmacy owner can be an example if they take the risk of dispensing a product without having tracing data.



Ian Cannell, practice lead consultant/DSCSA project manager at Kaiser Permanente, said that was the elephant in the room. “The question is, how not to grope on the one-yard line?” He agreed with the other panelists about getting supplies from another pharmacy or finding alternatives: “Can we place an overnight or emergency order? Can we choose another SKU? Is there another choice that can be used? I think your original question was largely about policy and procedure. Every organization needs to take a cold look at their compliance and legal department when it comes to whether you have a worst-case scenario, whether it’s compliance versus the reality of a critical business need. ‘a patient…it comes down to trying to mitigate those risks in advance.”

Cannell also noted that distributors have limited resources and limited serialization vendors. To avoid bottlenecks, the best practice is to try to move forward and identify trading partners with data issues ahead of time to try to mitigate these scenarios. But some partners can lose business if they put distributors at risk by not providing the correct product data.

Nevers added that precise upstream operations should help alleviate the problem. “So [product] arrives and we receive at the warehouse. If our employees scan and find “no data”, your data will not go any further and we will not pay you for it. It defeats the purpose of what we are working on together. He concluded that he did not intend to put his customers or pharmacists at risk by moving the product from the warehouse to stores when they have no data on where it came from.

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